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HMGBIOTECH DISULFIDE HMGB1說(shuō)明書

更新時(shí)間：2024-03-15 點(diǎn)擊次數(shù)：1193

HMGBIOTECH 高遷移率蛋白、質(zhì)粒、抗體

hmgbiotech HM-120

HMGB 1是細(xì)胞核的一個(gè)組成部分，在基因組的組織和表達(dá)中具有多種功能。HMG生物技術(shù)SRL為活躍在這一領(lǐng)域的其他研究人員和公司提供試劑、服務(wù)和想法。它還有助于實(shí)驗(yàn)室開(kāi)發(fā)分析和試劑。

hmgbiotech DISULFIDE HMGB1說(shuō)明書

hmgbiotech HM-120

HMGB1是一種核蛋白，其由壞死細(xì)胞被動(dòng)釋放，由凋亡細(xì)胞保留，并由炎癥細(xì)胞主動(dòng)分泌（Dumitriu等人，HMGB1:從內(nèi)部引導(dǎo)免疫。Trends Immunol 2005，26:381-7）。HMGB1對(duì)生命至關(guān)重要：HMGB1基因敲除小鼠出生后不久死亡。

HMGB1作為運(yùn)動(dòng)細(xì)胞的化學(xué)引誘劑和細(xì)胞因子的誘導(dǎo)劑的兩種不同活性被歸因于不同的生物化學(xué)形式。還原的HMGB1（具有化學(xué)引誘活性的形式）被還原；二硫化物HMGB1包含C23和C45之間的二硫鍵（完整注釋：HMGB1C23-C45C106h–Antoine J.等人（2014）。Mol-Med）。

二硫化物HMGB1可誘導(dǎo)單核細(xì)胞和其他炎癥細(xì)胞產(chǎn)生細(xì)胞因子和趨化因子（Venereau等人，2012）。

在結(jié)構(gòu)上，二硫化物HMGB1在半胱氨酸殘基23和45與還原的半胱氨酸殘基106之間具有二硫鍵。測(cè)試二硫化物HMGB1刺激細(xì)胞因子的能力

HMGBiotech公司熱銷產(chǎn)品

產(chǎn)品名稱	貨號(hào)
100 ug Fully reduced HMGB1, LPS free	HM-115
50 ug Fully reduced HMGB1, LPS free	HM-116
100 ug Disulfide HMGB1, LPS free	HM-121
100 ug BoxA from HMGB1, LPS-free and tested in migration assay	HM-012
50 ug Disulfide HMGB1, LPS free	HM-122
500 ug BoxA from HMGB1, LPS-free and tested in migration assay	HM-013
1 mg HMGB1 for biochemistry	HM-100
2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay	HM-014
250 ug HMGB1 biochemistry	HM-101
25 ug BoxA from HMGB1, LPS-free and tested in migration assay	HM-011
15 ug BoxB from HMGB1, LPS-free and tested in migration assay	HM-053
15 ug Fully reduced HMGB1, LPS free	HM-117
10 ug Disulfide HMGB1, LPS free	HM-123
15 ug Non-oxidizable HMGB1, LPS free	HM-133
250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration	HM-170
100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration	HM-171
50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration	HM-172
15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration	HM-173
50 ug HMGB1 15N labelled for Mass Spectrometry	HM-180
5 ug HMGB1 15N labelled for Mass Spectrometry	HM-181
2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay	HM-190
500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay	HM-191
100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay	HM-192
25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay	HM-193
Control cell lysates from Hmgb1 +/+	HM-001
Control cell lysates from Hmgb1 -/-	HM-002
1 mg BoxB from HMGB1, LPS-free and tested in migration assay	HM-050
250 ug BoxB from HMGB1, LPS-free and tested in migration assay	HM-051
100 ug BoxB from HMGB1, LPS-free and tested in migration assay	HM-052
500 ug Fully reduced HMGB1, LPS free	HM-114
250 ug Disulfide HMGB1, LPS free	HM-120
500 ug Non-oxidizable HMGB1, LPS free	HM-130
100 ug Non-oxidizable HMGB1, LPS free	HM-131
50 ug Non-oxidizable HMGB1, LPS free	HM-132
500 ug HMGB2, LPS-free and tested in migration assay	HM-151
100 ug HMGB2, LPS-free and tested in migration assay	HM-152
50 ug HMGB2, LPS-free and tested in migration assay	HM-153
Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells	HM-201
Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells	HM-221
Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and	HM-223
HMGB1 Isoforms Kit - Test size	HM-030
Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells	HM-251
HMGB1 Isoforms Kit - Regular size	HM-031
20 ug p-mHMG1	HM-300
50 ug Terminally oxidized HMGB1, LPS free	HM-062
20 ug p-mHMG1tag	HM-301
100 ug Terminally oxidized HMGB1, LPS free	HM-061
20 ug pEGFP-HMGB1	HM-302
250 ug Terminally oxidized HMGB1, LPS free	HM-060
20 ug pcDNA/FL-RAGE plasmid	HM-310

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