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            當前位置:首頁 > 技術文章 > listlabs 炭疽毒素說明書

            listlabs 炭疽毒素說明書

            更新時間:2018-12-10      點擊次數:3235

            list biological laboratories公司是世界的科研毒素試劑供應商,其毒素包括霍亂病毒,蛇毒,百日咳毒素等各類毒素,我公司常年低價供應,貨期快.有意者請. 百日咳毒素長期現貨供應,貨號181及180

             

            listlabs 炭疽毒素說明書

            炭疽毒素Anthrax Toxins

             

            炭疽桿菌是炭疽病的病原體。炭疽桿菌產生的主要毒力因子是γ連接的聚-D-谷氨酸膠囊和由三種成分組成的外毒素,保護性抗原(PA),致死因子(LF)和水腫因子(EF)。這些蛋白質不是單*毒的,而是以二元組合起作用。PA(細胞結合成分)與LF(酶部分之一)的復合物被稱為“致死毒素”并可導致死亡。PA和酶促EF一起引起皮膚水腫。分泌后,PA被膜肽酶切割,使63kDa羧基末端片段寡聚化成七聚體。切割是暴露EF和LF的結合位點的必要步驟。組裝的PA復合物和相關的LF或EF通過胞吞作用進入細胞。PA介導LF和EF向細胞質的轉移,其中這些酶識別并蛋白水解其靶標。LF組分是一種鋅依賴性金屬蛋白酶,可裂解絲裂原活化蛋白激酶激酶(MAPKK),從而削弱其功能,從而阻斷MAPK信號通路。EF是鈣調蛋白依賴性腺苷酸環化酶,其在細胞中產生過量的環AMP,導致水腫。目前的研究集中于開發有效的疫苗以及篩選LF酶活性的有效抑制劑。

            含有炭疽LF切割位點的FRET肽底物可作為MAPKKide®獲得,并可用于評估LF的酶活性。

            炭疽毒素

            (炭疽水腫因子)

            水腫因子(EF)是鈣調蛋白依賴性腺苷酸環化酶,其可在易感細胞內產生過量的腺苷酸環化酶。List Labs提供兩種形式的EF,它們都是在天然炭疽芽孢桿菌宿主中重組制備的。產物#178由天然序列組成,在N-末端具有另外的氨基酸組氨酸。產物#173的突變體EF S414N具有降低的腺苷酸環化酶活性,并且已顯示其充當佐劑。

            炭疽毒素

            (炭疽水腫因子)

             

            炭疽水腫因子(EF),來自炭疽桿菌的
            重組體

            窗體頂端

            產品#和尺寸

            #178A(0.1毫克) - 160.00美元

             

             

             

            炭疽毒素

            (炭疽水腫因子)

             

            來自炭疽芽孢桿菌的炭疽水腫因子(EF),
            重組,突變體S447N

             

            產品#和尺寸

            #173B(0.5毫克) - 950.00美元

             

             

            貨號

            品名

             規格

            價格

            list104

            Cholera Toxin B Subunit (Choleragenoid) in low salt1

            0.5mg

            4930

            list106

            Cholera Toxin B Subunit Fluorescein Isothiocyanate Conjugate (BFITC)

            0.2mg

            9775

            list112

            Cholera Toxin B Subunit Biotin

            0.2mg

            9775

            list122

            Enterotoxin Type B from Staphylococcus aureus1,3

            0.5mg

            7225

            list123

            Enterotoxin Type B Toxoid from Staphylococcus aureus  1,3

            0.25mg

            8075

            list139

            Botulinum Neurotoxin Type B Toxoid

            10µg

            6800

            list150

            Diphtheria Toxin, unnicked from Corynebacterium diphtheriae

            1mg

            11050

            list151

            Diphtheria Toxoid, from Corynebacterium diphtheriae

            0.5mg

            10625

            list153

            Toxin A Toxoid from Clostridium difficile

            100µg

            11900

            list156

            Pasteurella Multocida Toxin

            50µg

            8075

            list160

            Exotoxin A from Pseudomonas aeruginosa

            1mg

            4420

            list161

            Shiga Toxin 1 from Escherichia coli1,4,8

            10µg

            11900

            list162

            Shiga Toxin 2 from Escherichia coli1,4,8

            10µg

            11050

            list174

            Anthrax Protective Antigen, Activated (PA 63) from Bacillus anthracis

            0.5mg

            9350

            list175

            Anthrax PA 63 - Fluorescein Isothiocyanate Conjugate (PAFITC)

            50µg

            7225

            list180

            Pertussis Toxin Islet-Activating Protein Lyophilized in buffer

            50µg

            5525

            list181

            Pertussis Toxin Islet Activating Protein Lyophilized (Salt-Free)

            50µg

            5525

            list184

            Pertussis Toxin Mutant

            50µg

            5525

            list186

            FIMBRIAE 2/3 from B. pertussis

            50µg

            5950

            list187

            Pertactin from Bordetella pertussus (69 kDa Protein)

            50µg

            4590

            list193

            Tetanus Toxin C Fragment

            10µg

            9350

            list201

            LPS from Escherichia coli O111:B4

            5mg

            3230

            list206

            LPS, Escherichia coli 0157:H7

            10.0mg

            4760

            list225

            LPS from Salmonella typhimurium

            5mg

            2890

            list301

            LPS from Escherichia coli J5 (Rc)

            5mg

            2890

            list302

            LPS from Escherichia coli K12, D31m4 (Re)

            5mg

            2890

            list304

            LPS from Salmonella minnesota R595 (Re)

            5mg

            2890

            list314

            LPS from Escherichia coli K12 strain LCD25

            1mg

            2890

            list400

            HPT™ LPS, highly purified from Bordetella Pertussis 165

            1mg

            5100

            list401

            Lipid A monophosphoryl from Salmonella minnesota R595

            1mg

            3400

            list421

            Ultra Pure LPS from Escherichia coli O111:B4

            1mg

            3570

            list423

            Ultra Pure LPS from Escherichia coli O55:B5

            1mg

            3570

            list433

            LISTÔ HPTÔ, LPS, highly purified Escherichia coli O113 LPS

            1mg

            4080

            list434

            Ultra Pure LPS from Salmonella minnesota R595 (Re)

            1mg

            3400

            list520

            SNAPtide® Peptide Substrate (o-Abz/Dnp)  (U.S. Patent #6,504,006)

            200nmoles

            9775

            list521

            SNAPtide® Peptide Substrate (FITC/DABCYL)  (U.S. Patent #6,504,006)

            200nmoles

            8500

            list523

            SNAPtideÒ Peptide Substrate flP6 (DABCYL/5-IAF), U.S. Patent Pending #61/252,675

            200nmoles

            8500

            list525

            Control Peptide for SNAPtideÒ #520

            200nmoles

            8500

            list526

            Control Peptide for SNAPtide® #521

            200nmoles

            8500

            list528

            Unquenched Calibration Peptide for SNAPtide®  521

            50nmoles

            2890

            list529

            Unquenched Calibration Peptide for SNAPtide®  520

            50nmoles

            2890

            list530

            MAPKKide® Peptide Substrate (o-Abz/Dnp)

            200nmoles

            5100

            list531

            MAPKKide® Peptide Substrate  (DABCYL/FITC)

            200nmoles

            5100

            list532

            MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor

            100nmoles

            4250

            list539

            Unquenched Calibration Peptide for MAPKKideÒ 530

            50nmoles

            2890

            list540

            VAMPtide® Peptide Substrate (o-Abz/Dnp)

            200nmoles

            8500

            list541

            VAMPtide® Peptide Substrate (FITC/DABCYL)

            200nmoles

            8500

            list542

            VAMPtide® Peptide Substrate (PL 150, Pya/Nop)

            200nmoles

            8500

            list549

            Calibration  Fluorophore for VAMPtideÒ 540

            100nmoles

            2890

            list550

            SNAP Etide® Peptide Substrate (o-Abz/Dnp)

            100nmoles

            6800

            list560

            SYNTAXtideÒ Peptide Substrate (o-Abz/Dnp) for C. botulinum Type C

            200nmoles

            8500

            list703

            Anti-Cholera Toxin B Subunit (Goat)

            0.1ml

            3060

            list752

            Anti-Toxin A from Clostridium difficile (Goat)

            0.5ml

            3230

            list760

            Anti-Exotoxin A (Goat)

            0.5ml

            3400

            list781

            Anti-Protective Antigen from Bacillus anthracis (Goat) affinity purified, Liquid6,7

            0.1mg

            7055

            list100B

            Cholera Toxin (Azide Free)1

            1mg

            3400

            list101B

            Cholera Toxin1

            1mg

            3400

            list101C

            Cholera Toxin1

            2mg

            5355

            list116L

            Alpha Toxin from C. septicum4,6,7

            50µg

            4930

            list126A

            Epsilon Toxin from C. perfringens1,4,8

            0.1mg

            5950

            list128A

            Botulinum Neurotoxin Type A Complex from Clostridium botulinum1,3

            10µg

            2890

            list128C

            Botulinum Neurotoxin Type A Complex from Clostridium botulinum1,3

            100µg

            5440

            list130A

            Botulinum Neurotoxin Type A from Clostridium botulinum1,3

            10µg

            5440

            list130B

            Botulinum Neurotoxin Type A from Clostridium botulinum1,3

            100µg

            13600

            list133L

            Botulinum Neurotoxin Type A Toxoid, Liquid6,7

            10µg

            5440

            list136A

            Botulinum Neurotoxin Type B. from Clostridium botulinum 1,3

            10µg

            5100

            list136B

            Botulinum Neurotoxin Type B, from Clostridium botulinum1,3

            100µg

            17000

            list138A

            Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum1,3

            10µg

            2890

            list138B

            Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum1,3

            100µg

            7225

            list140A

            Botulinum Neurotoxin Type E, Nicked, Complex from Clostridium botulinum1,3

            10µg

            2890

            list140B

            Botulinum Neurotoxin Type E, Nicked, Complex from Clostridium botulinum1,3

            100µg

            8925

            list141A

            Botulinum Neurotoxin Type E, Nicked, from Clostridium botulinum1,3

            10µg

            8075

            list146A

            Botulinum Neurotoxin Type D, Nicked, Recombinant from Clostridium botulinum1,3

            10µg

            5355

            list149A

            Diphtheria Toxin CRM Mutant

            0.25 mg

            8500

            list152C

            Toxin A from Clostridium difficile

            100µg

            9010

            list154A

            Toxin B Toxoid from Clostridium difficile

            20µg

            2890

            list15

            Toxin B  from Clostridium difficile

            2µg

            2890

            list155B

            Toxin B  from Clostridium difficile

            20µg

            8500

            list155C

            Toxin B  from Clostridium difficile

            200µg

            15300

            list155L

            Toxin B from Clostridium difficile, Liquid6,7

            50µg

            9860

            list157A

            Binary  Toxin from Clostridium difficile, A Subunit

            20µg

            5950

            list158A

            Binary  Toxin from Clostridium difficile, B Subunit

            40µg

            5950

            list159A

            Glutamate Dehydrogenase (GDH) from Clostridium difficile6,7

            0.1mg

            4930

            list169A

            Anthrax Lethal Factor (LF-A) , Recombinant from Bacillus anthracis Native Sequence

            0.1mg

            3060

            list169B

            Anthrax Lethal Factor (LF-A),Recombinant from Bacillus anthracis Native Sequence

            1mg

            12750

            list169L

             Anthrax Lethal Factor (LF-A),Recomb.from Bacillus anthracis 5,7

            0.2 mg

            5950

            list171E

            Anthrax Protective Antigen (PA), Recombinant from Bacillus anthracis

            0.5mg

            8755

            list172B

            Anthrax Lethal Factor (LF), Recombinant from Bacillus anthracis

            1mg

            12750

            list172C

            Anthrax Lethal Factor (LF), Recombinant from Bacillus anthracis

            10mg

            39525

            list172L

            Lethal Factor, Recomb from Bacillus anthracis, froz liq 5,7

            1.0 mg

            12750

            list173B

            Anthrax Edema Factor (EF), Recombinant Mutant S447N  from Bacillus anthracis

            0.5mg

            16150

            list176A

            Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from Bacillus anthracis

            0.1mg

            5100

            list176B

            Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from Bacillus anthracis

            1mg

            16150

            list177A

            Anthrax Protective Antigen Fragment (PA 20) from Bacillus anthracis

            50µg

            5950

            list177B

            Anthrax Protective Antigen Fragment (PA 20) from Bacillus anthracis

             0.25mg

            11050

            list178A

            Anthrax Edema Factor (EF), Recombinant from Bacillus anthracis

            0.1mg

            2890

            list179A

            Pertussis Toxin Islet Activating Protein (in glycerol)6,7

            50µg

            4845

            list188L

            Adenylate Cyclase Toxin from B. pertussis, Recombinant, Frozen Liquid5,7

            50µg

            5270

            list190A

            Tetanus Toxin2

            25µg

            2890

            list190B

            Tetanus Toxin2

            100µg

            9350

            list191A

            Tetanus Toxoid

            25µg

            4675

            list191B

            Tetanus Toxoid

            100µg

            13600

            list196A

            C-fragment, FITC Conjugate

            10µg

            6800

            list203A

            LPS, Escherichia coli O55:B5

            2.5 mg

            3060

            list500A

            SNAP-25 Recomb Protein Substrate for C. botulinum Type A and E Neurotoxin

            100µg

            5525

            list510A

            GST Synaptobrevin-2 Protein Recomb. Protein Substrate for C. botulinum Type B,D and F

            100µg

            5950

            list610A

            Botulinum Neurotoxin Type A Light Chain, Recombinant1

            10µg

            4760

            list611A

            Botulinum Neurotoxin Type A Light Chain, GST Fusion, Recombinant1

            15µg

            4760

            list612A

            Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain1

            50µg

            4760

            list613A

            Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain, GST Fusion1

            50µg

            4760

            list620A

            Botulinum Neurotoxin Type B Light Chain, Recombinant1

            10µg

            8500

            list622A

            Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain1

            50µg

            4760

            list623A

            Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain, GST Fusion1

            50µg

            4760

            list62

            Botulinum Neurotoxin Type C Light Chain, Recombinant1

            10µg

            8500

            list630A

            Botulinum Neurotoxin Type D Light Chain, Recombinant1

            10µg

            5695

            list650A

            Tetanus Toxin Light Chain, Recombinant

            10µg

            3825

            list690B

            Receptor for C. botulinum Type A Neurotoxin GST-SV2c luminal domain
            (U.S. Patent #8,476,024)

            100nmoles

            6800

            list730A

            Anti-Botulinum Neurotoxin, Type A (Chicken lgY), Liquid6,7

            0.1mg

            5610

            list731L

            Anti-Botulinum Neurotoxin, Type A (Mouse lgG monoclonal F1-40), Liquid6,7

            0.1mg

            5950

            list736A

            Anti-Botulinum Type B (Chicken lgY), Liquid6,7

            0.1mg

            5950

            list753A

            Anti-Clostridium difficile Toxin A (Chicken lgY), Liquid6,7

            0.1mg

            5780

            list754A

            Anti-Clostridium difficile Toxin B (Chicken lgY), Liquid6,7

            0.1mg

            5780

            list756A

            Anti-Clostridium difficile Glutamate Dehydrogenase, lgY, Liquid6,7

            0.1mg

            5780

            list757A

            Anti-Clostridium difficile Binary Toxin A subunit (Chicken lgY), Liquid6,7

            0.1mg

            5780

            list758A

            Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY), Liquid6,7

            0.1mg

            5780

            list759A

            Biotinylated Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY), Liquid6,7

            0.1mg

            5780

            list761L

            Anti-Shiga Toxin 1 (Rabbit), lgG, Liquid6,7

            0.5mg

            3400

            list765L

            Anti-Shiga Toxin 2 (Rabbit), IgG, Liquid6,7

            0.5mg

            2890

            list766L

            Anti-Shiga Toxin, Camelid Antibody, VHH, Liquid6,7

            0.5mg/ml

            5950

            list768L

            Biotinylated Anti-Lethal Factor from B. anthracis, IgY, Liquid6,7

            0.1mg

            5950

            list769B

            Anti-Lethal Factor from Bacillus anthracis (Chicken lgY), Liquid6,7

            0.2mg

            8500

            list771B

            Anti-Protective Antigen from Bacillus anthracis (Goat)

            1mg

            2890

            list772B

            Anti-Lethal Factor from Bacillus anthracis (Goat)

            1.0 mg

            2890

            list773L

            Anti-Edema Factor from Bacillus anthracis (Goat), Liquid6,7

            1mg

            2890

             

             

             

            Listlabs中國代理,Listlabs上海代理,Listlabs北京代理,Listlabs廣東代理,Listlabs江蘇代理Listlabs湖北代理,Listlabs天津代理,Listlabs黑龍江代理,Listlabs湖南代理Listlabs內蒙古代理,Listlabs吉林代理,Listlabs福建代理,Listlabs江蘇代理,Listlabs浙江代理,Listlabs四川代理,Listlabs代理,

             

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